Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics

Wilbur Johnson; Wilma F. Bergfeld; Donald V. Belsito; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Lisa A. Peterson; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice M. Fiume; Bart Heldreth

doi:10.1177/10915818251350378

Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics

Wilbur Johnson, Wilma F. Bergfeld, Donald V. Belsito, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Lisa A. Peterson, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Monice M. Fiume, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 4 Scutellaria baicalensis-derived ingredients in cosmetic products; these ingredients are reported to have the following functions in cosmetics: antimicrobial agent, skin conditioning agent, abrasives, fragrance ingredients, skin protectants, and antioxidants. The Panel reviewed relevant data relating to the safety of these ingredients in cosmetic formulations, and concluded that Scutellaria Baicalensis Root Extract and Scutellaria Baicalensis Root Powder are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination of safety for Scutellaria Baicalensis Extract and Scutellaria Baicalensis Sprout Extract under the reported conditions of use in cosmetic formulations.

Original language	English (US)
Pages (from-to)	124S-138S
Journal	International journal of toxicology
Volume	44
Issue number	2
DOIs	https://doi.org/10.1177/10915818251350378
State	Published - Aug 2025

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818251350378

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Johnson, W., Bergfeld, W. F., Belsito, D. V., Klaassen, C. D., Liebler, D. C., Marks, J. G., Peterson, L. A., Shank, R. C., Slaga, T. J., Snyder, P. W., Fiume, M. M., & Heldreth, B. (2025). Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics. International journal of toxicology, 44(2), 124S-138S. https://doi.org/10.1177/10915818251350378

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title = "Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 4 Scutellaria baicalensis-derived ingredients in cosmetic products; these ingredients are reported to have the following functions in cosmetics: antimicrobial agent, skin conditioning agent, abrasives, fragrance ingredients, skin protectants, and antioxidants. The Panel reviewed relevant data relating to the safety of these ingredients in cosmetic formulations, and concluded that Scutellaria Baicalensis Root Extract and Scutellaria Baicalensis Root Powder are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination of safety for Scutellaria Baicalensis Extract and Scutellaria Baicalensis Sprout Extract under the reported conditions of use in cosmetic formulations.",

author = "Wilbur Johnson and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Peterson, \{Lisa A.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Fiume, \{Monice M.\} and Bart Heldreth",

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year = "2025",

month = aug,

doi = "10.1177/10915818251350378",

language = "English (US)",

volume = "44",

pages = "124S--138S",

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AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Peterson, Lisa A.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice M.

AU - Heldreth, Bart

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AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 4 Scutellaria baicalensis-derived ingredients in cosmetic products; these ingredients are reported to have the following functions in cosmetics: antimicrobial agent, skin conditioning agent, abrasives, fragrance ingredients, skin protectants, and antioxidants. The Panel reviewed relevant data relating to the safety of these ingredients in cosmetic formulations, and concluded that Scutellaria Baicalensis Root Extract and Scutellaria Baicalensis Root Powder are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination of safety for Scutellaria Baicalensis Extract and Scutellaria Baicalensis Sprout Extract under the reported conditions of use in cosmetic formulations.

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Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics

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