Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics

Priya Cherian; Wilma F. Bergfeld; Donald V. Belsito; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Lisa A. Peterson; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice Fiume; Bart Heldreth

doi:10.1177/10915818241231249

Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics

Priya Cherian, Wilma F. Bergfeld, Donald V. Belsito, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Lisa A. Peterson, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Monice Fiume, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 28 soy-derived ingredients as used in cosmetic products. These ingredients are reported to primarily function as antioxidants, skin protectants, skin-conditioning agents, and hair-conditioning agents. The Panel considered the available data relating to the safety of these ingredients in cosmetic formulations, and concluded that 24 of the 28 soy-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination that Glycine Max (Soybean) Callus Culture, Glycine Max (Soybean) Callus Culture Extract, Glycine Max (Soybean) Callus Extract, and Glycine Max (Soybean) Phytoplacenta Conditioned Media are safe under the intended conditions of use in cosmetic formulations.

Original language	English (US)
Pages (from-to)	64S-85S
Journal	International journal of toxicology
Volume	44
Issue number	1_suppl
DOIs	https://doi.org/10.1177/10915818241231249
State	Published - Feb 2025

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818241231249

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title = "Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 28 soy-derived ingredients as used in cosmetic products. These ingredients are reported to primarily function as antioxidants, skin protectants, skin-conditioning agents, and hair-conditioning agents. The Panel considered the available data relating to the safety of these ingredients in cosmetic formulations, and concluded that 24 of the 28 soy-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination that Glycine Max (Soybean) Callus Culture, Glycine Max (Soybean) Callus Culture Extract, Glycine Max (Soybean) Callus Extract, and Glycine Max (Soybean) Phytoplacenta Conditioned Media are safe under the intended conditions of use in cosmetic formulations.",

author = "Priya Cherian and Bergfeld, {Wilma F.} and Belsito, {Donald V.} and Klaassen, {Curtis D.} and Liebler, {Daniel C.} and Marks, {James G.} and Peterson, {Lisa A.} and Shank, {Ronald C.} and Slaga, {Thomas J.} and Snyder, {Paul W.} and Monice Fiume and Bart Heldreth",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2025",

month = feb,

doi = "10.1177/10915818241231249",

language = "English (US)",

volume = "44",

pages = "64S--85S",

journal = "International journal of toxicology",

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AU - Cherian, Priya

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Peterson, Lisa A.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice

AU - Heldreth, Bart

PY - 2025/2

Y1 - 2025/2

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AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 28 soy-derived ingredients as used in cosmetic products. These ingredients are reported to primarily function as antioxidants, skin protectants, skin-conditioning agents, and hair-conditioning agents. The Panel considered the available data relating to the safety of these ingredients in cosmetic formulations, and concluded that 24 of the 28 soy-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination that Glycine Max (Soybean) Callus Culture, Glycine Max (Soybean) Callus Culture Extract, Glycine Max (Soybean) Callus Extract, and Glycine Max (Soybean) Phytoplacenta Conditioned Media are safe under the intended conditions of use in cosmetic formulations.

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JO - International journal of toxicology

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IS - 1_suppl

ER -

Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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