Sample size for testing difference between two proportions for the bilateral-sample design

Shi Fang Qiu, Nian Sheng Tang, Man Lai Tang, Yan Bo Pei

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In this article, we consider approximate sample size formulas for testing difference between two proportions for bilateral studies with binary outcomes. Sample size formulas are derived to achieve a prespecified power of a statistical test at a prechosen significance level. Four statistical tests are considered. Simulation studies are conducted to investigate the accuracy of various formulas. In general, the sample size formula for Rosner's statistic based on the dependence assumption is highly recommended in the sense that its actual power is satisfactorily close to the desired power level. An example from an otolaryngological study is used to demonstrate the proposed methodologies.

Original languageEnglish (US)
Pages (from-to)857-871
Number of pages15
JournalJournal of Biopharmaceutical Statistics
Volume19
Issue number5
DOIs
StatePublished - Sep 2009

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Pharmacology
  • Pharmacology (medical)

Fingerprint

Dive into the research topics of 'Sample size for testing difference between two proportions for the bilateral-sample design'. Together they form a unique fingerprint.

Cite this