Scar sarcoidosis following rituximab therapy

Nicole C. Vesely; Renee M. Thomas; Eric Rudnick; Maria Isabel Longo

doi:10.1111/dth.13693

Scar sarcoidosis following rituximab therapy

Nicole C. Vesely, Renee M. Thomas, Eric Rudnick, Maria Isabel Longo

Department of Dermatology

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10 Scopus citations

Abstract

Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report a case of rituximab-induced scar sarcoidosis and review similar published cases. Although there is evidence of B-cell dysregulation in the pathogenesis of sarcoidosis, the use of rituximab for this disease needs to be carefully evaluated based on reports of worsening and de novo development of sarcoidosis after rituximab therapy.

Original language	English (US)
Article number	e13693
Journal	Dermatologic Therapy
Volume	33
Issue number	6
DOIs	https://doi.org/10.1111/dth.13693
State	Published - Nov 1 2020

All Science Journal Classification (ASJC) codes

Dermatology

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10.1111/dth.13693

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title = "Scar sarcoidosis following rituximab therapy",

abstract = "Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report a case of rituximab-induced scar sarcoidosis and review similar published cases. Although there is evidence of B-cell dysregulation in the pathogenesis of sarcoidosis, the use of rituximab for this disease needs to be carefully evaluated based on reports of worsening and de novo development of sarcoidosis after rituximab therapy.",

author = "Vesely, {Nicole C.} and Thomas, {Renee M.} and Eric Rudnick and Longo, {Maria Isabel}",

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AU - Vesely, Nicole C.

AU - Thomas, Renee M.

AU - Rudnick, Eric

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N2 - Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report a case of rituximab-induced scar sarcoidosis and review similar published cases. Although there is evidence of B-cell dysregulation in the pathogenesis of sarcoidosis, the use of rituximab for this disease needs to be carefully evaluated based on reports of worsening and de novo development of sarcoidosis after rituximab therapy.

AB - Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report a case of rituximab-induced scar sarcoidosis and review similar published cases. Although there is evidence of B-cell dysregulation in the pathogenesis of sarcoidosis, the use of rituximab for this disease needs to be carefully evaluated based on reports of worsening and de novo development of sarcoidosis after rituximab therapy.

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Scar sarcoidosis following rituximab therapy

Abstract

All Science Journal Classification (ASJC) codes

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