SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM

John R. Fenyk; Phyllis I. Warkentin; Robert W. Goltz; Mark E. Nesbit; Peter F. Coccia; Clark M. Smith; William Krivit; John E. Neely; Norma K.C. Ramsay; John H. Kersey

doi:10.1016/S0140-6736(78)90136-8

SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM

John R. Fenyk, Phyllis I. Warkentin, Robert W. Goltz, Mark E. Nesbit, Peter F. Coccia, Clark M. Smith, William Krivit, John E. Neely, Norma K.C. Ramsay, John H. Kersey

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43 Scopus citations

Abstract

A female patient with severe idiopathic aplastic anæmia received a successful bone-marrow transplant from her HLA-identical, mixed-lymphocyte-culture-compatible, brother. 8 months after transplantation she had localised cutaneous measles. Chronic sclerodermatous changes developed which were indistinguishable from chronic graft-versus-host disease and were limited to the areas of the original exanthem. Interaction between viral infection and minor histocompatibility differences probably resulted in graft-versus-host disease in this patient.

Original language	English (US)
Pages (from-to)	472-473
Number of pages	2
Journal	The Lancet
Volume	311
Issue number	8062
DOIs	https://doi.org/10.1016/S0140-6736(78)90136-8
State	Published - Mar 4 1978

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General Medicine

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10.1016/S0140-6736(78)90136-8

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title = "SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM",

abstract = "A female patient with severe idiopathic aplastic an{\ae}mia received a successful bone-marrow transplant from her HLA-identical, mixed-lymphocyte-culture-compatible, brother. 8 months after transplantation she had localised cutaneous measles. Chronic sclerodermatous changes developed which were indistinguishable from chronic graft-versus-host disease and were limited to the areas of the original exanthem. Interaction between viral infection and minor histocompatibility differences probably resulted in graft-versus-host disease in this patient.",

author = "Fenyk, {John R.} and Warkentin, {Phyllis I.} and Goltz, {Robert W.} and Nesbit, {Mark E.} and Coccia, {Peter F.} and Smith, {Clark M.} and William Krivit and Neely, {John E.} and Ramsay, {Norma K.C.} and Kersey, {John H.}",

note = "Funding Information: by U.S.P.H.S. grants T32-AM07165, CA18083, CA16228, CA15548, and contract CP43384.",

year = "1978",

month = mar,

day = "4",

doi = "10.1016/S0140-6736(78)90136-8",

language = "English (US)",

volume = "311",

pages = "472--473",

journal = "The Lancet",

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publisher = "Elsevier B.V.",

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T1 - SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM

AU - Fenyk, John R.

AU - Warkentin, Phyllis I.

AU - Goltz, Robert W.

AU - Nesbit, Mark E.

AU - Coccia, Peter F.

AU - Smith, Clark M.

AU - Krivit, William

AU - Neely, John E.

AU - Ramsay, Norma K.C.

AU - Kersey, John H.

N1 - Funding Information: by U.S.P.H.S. grants T32-AM07165, CA18083, CA16228, CA15548, and contract CP43384.

PY - 1978/3/4

Y1 - 1978/3/4

N2 - A female patient with severe idiopathic aplastic anæmia received a successful bone-marrow transplant from her HLA-identical, mixed-lymphocyte-culture-compatible, brother. 8 months after transplantation she had localised cutaneous measles. Chronic sclerodermatous changes developed which were indistinguishable from chronic graft-versus-host disease and were limited to the areas of the original exanthem. Interaction between viral infection and minor histocompatibility differences probably resulted in graft-versus-host disease in this patient.

AB - A female patient with severe idiopathic aplastic anæmia received a successful bone-marrow transplant from her HLA-identical, mixed-lymphocyte-culture-compatible, brother. 8 months after transplantation she had localised cutaneous measles. Chronic sclerodermatous changes developed which were indistinguishable from chronic graft-versus-host disease and were limited to the areas of the original exanthem. Interaction between viral infection and minor histocompatibility differences probably resulted in graft-versus-host disease in this patient.

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SCLERODERMATOUS GRAFT-VERSUS-HOST DISEASE LIMITED TO AN AREA OF MEASLES EXANTHEM

Abstract

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