TY - JOUR
T1 - Scleromyxedema presenting with neurologic symptoms
T2 - A case report and review of the literature
AU - Marshal, Kathleen
AU - Klepeiss, Stacy A.
AU - Ioffreda, Michael D.
AU - Helm, Klaus F.
PY - 2010/3
Y1 - 2010/3
N2 - Scleromyxedema is a rare variant of lichen myxedematosus. In addition to cutaneous manifestations, scleromyxedema often presents with systemic manifestations, including dysphagia, proximal muscle weakness, central nervous system disturbances, encephalopathy, and restrictive lung disease. It is almost always associated with paraproteinemia, usually IgG with γ light chains. We review the literature on scleromyxedema associated with neurologic symptoms and present a case of a 49-year-old woman with encephalopathy attributable to scleromyxedema.
AB - Scleromyxedema is a rare variant of lichen myxedematosus. In addition to cutaneous manifestations, scleromyxedema often presents with systemic manifestations, including dysphagia, proximal muscle weakness, central nervous system disturbances, encephalopathy, and restrictive lung disease. It is almost always associated with paraproteinemia, usually IgG with γ light chains. We review the literature on scleromyxedema associated with neurologic symptoms and present a case of a 49-year-old woman with encephalopathy attributable to scleromyxedema.
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M3 - Article
C2 - 20408512
AN - SCOPUS:77952308641
SN - 0011-4162
VL - 85
SP - 137
EP - 140
JO - Cutis
JF - Cutis
IS - 3
ER -