TY - JOUR
T1 - Segmentation of the central-chest lymph nodes in 3D MDCT images
AU - Lu, Kongkuo
AU - Higgins, William E.
N1 - Funding Information:
This work was partially supported by Grants R01-CA074325, R01-CA151433, and R44-CA091534 from the National Cancer Institute (NCI) of the National Institutes of Health (NIH). The NIH NCI had no involvement in the design of methods and studies in this paper. Pinyo Taeprasartsit served as an operator for the test of Section 3.
PY - 2011/9
Y1 - 2011/9
N2 - Central-chest lymph nodes play a vital role in lung-cancer staging. The definition of lymph nodes from three-dimensional (3D) multidetector computed-tomography (MDCT) images, however, remains an open problem. We propose two methods for computer-based segmentation of the central-chest lymph nodes from a 3D MDCT scan: the single-section live wire and the single-click live wire. For the single-section live wire, the user first applies the standard live wire to a single two-dimensional (2D) section after which automated analysis completes the segmentation process. The single-click live wire is similar but is almost completely automatic. Ground-truth studies involving human 3D MDCT scans demonstrate the robustness, efficiency, and intra-observer and inter-observer reproducibility of the methods.
AB - Central-chest lymph nodes play a vital role in lung-cancer staging. The definition of lymph nodes from three-dimensional (3D) multidetector computed-tomography (MDCT) images, however, remains an open problem. We propose two methods for computer-based segmentation of the central-chest lymph nodes from a 3D MDCT scan: the single-section live wire and the single-click live wire. For the single-section live wire, the user first applies the standard live wire to a single two-dimensional (2D) section after which automated analysis completes the segmentation process. The single-click live wire is similar but is almost completely automatic. Ground-truth studies involving human 3D MDCT scans demonstrate the robustness, efficiency, and intra-observer and inter-observer reproducibility of the methods.
UR - http://www.scopus.com/inward/record.url?scp=80051666685&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80051666685&partnerID=8YFLogxK
U2 - 10.1016/j.compbiomed.2011.06.014
DO - 10.1016/j.compbiomed.2011.06.014
M3 - Article
C2 - 21752358
AN - SCOPUS:80051666685
SN - 0010-4825
VL - 41
SP - 780
EP - 789
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
IS - 9
ER -
