Selective Sweeps

Z. A. Szpiech; R. D. Hernandez

doi:10.1016/B978-0-443-15750-9.20053-0

Selective Sweeps

Z. A. Szpiech
, R. D. Hernandez

Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The model of a de novo adaptive mutation arising in a population and rising to high frequency is referred to as a selective sweep and has been the subject of much theoretical study. Here we describe the basic model, the expected genetic patterns that result from such a process, and two major classes of statistics designed to infer genomic locations that have recently experienced a selective sweep (those based on the site frequency spectrum and those based on haplotype patterns). We conclude by discussing caveats to the model and possible alternatives that are gaining traction in the field.

Original language	English (US)
Title of host publication	Encyclopedia of Evolutionary Biology
Publisher	Elsevier
Pages	V2:388-V2:398
ISBN (Electronic)	9780443157509
ISBN (Print)	9780443157516
DOIs	https://doi.org/10.1016/B978-0-443-15750-9.20053-0
State	Published - Jan 1 2025

All Science Journal Classification (ASJC) codes

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
General Medicine

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10.1016/B978-0-443-15750-9.20053-0

Cite this

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Selective Sweeps

Abstract

All Science Journal Classification (ASJC) codes

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