Self-powered microscale pumps based on analyte-initiated depolymerization reactions

Hua Zhang, Kimy Yeung, Jessica S. Robbins, Ryan A. Pavlick, Meng Wu, Ran Liu, Ayusman Sen, Scott T. Phillips

Research output: Contribution to journalArticlepeer-review

84 Scopus citations


Pump it up: Insoluble polymer films that depolymerize to release soluble monomeric products when exposed to a specific analyte act as a microscale pump. Products formed as a result of depolymerization amplify the signal and create a concentration gradient that pumps fluids and insoluble particles away from the bulk polymer by a diffusiophoretic mechanism. These pumps can respond to a variety of analytes, from small molecules to enzymes.

Original languageEnglish (US)
Pages (from-to)2400-2404
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number10
StatePublished - Mar 5 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry


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