Serological identification of an Ir-region product

Věra Hauptfeld; Dagmar Klein; Jan Klein

doi:10.1126/science.181.4095.167

Serological identification of an Ir-region product

Věra Hauptfeld, Dagmar Klein, Jan Klein

Biology

Research output: Contribution to journal › Article › peer-review

122 Scopus citations

Abstract

Reciprocal immunization of congenic lines differing in the middle portion of the H-2 complex leads to the production of antibodies which react with an antigen or antigens controlled by the Ir region. The antigen designated Ir-1.1 seems to be present only on a subpopulation of lymphocytes from lymph nodes and spleen. It is absent on bone marrow cells.

Original language	English (US)
Pages (from-to)	167-168
Number of pages	2
Journal	Science
Volume	181
Issue number	4095
DOIs	https://doi.org/10.1126/science.181.4095.167
State	Published - 1973

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title = "Serological identification of an Ir-region product",

abstract = "Reciprocal immunization of congenic lines differing in the middle portion of the H-2 complex leads to the production of antibodies which react with an antigen or antigens controlled by the Ir region. The antigen designated Ir-1.1 seems to be present only on a subpopulation of lymphocytes from lymph nodes and spleen. It is absent on bone marrow cells.",

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AB - Reciprocal immunization of congenic lines differing in the middle portion of the H-2 complex leads to the production of antibodies which react with an antigen or antigens controlled by the Ir region. The antigen designated Ir-1.1 seems to be present only on a subpopulation of lymphocytes from lymph nodes and spleen. It is absent on bone marrow cells.

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Serological identification of an Ir-region product

Abstract

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