TY - JOUR
T1 - Serum vitamin D and cognition in a cohort of Boston-area Puerto Ricans
AU - Palacios, Natalia
AU - Scott, Tammy
AU - Sahasrabudhe, Neha
AU - Gao, Xiang
AU - Tucker, Katherine L.
N1 - Publisher Copyright:
© 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Background: Vitamin D has been suggested as a protective factor for cognitive health, however results of prior studies have been mixed. To examine whether serum 25(OH)D concentration is related to cognition and cognitive decline in a study of Boston Area Puerto Ricans. Methods: We examined the association between serum 25(OH)D, cognitive function and cognitive decline in a longitudinal study of 967 Boston Area Puerto Rican adults. Results: In analyses adjusted for potential confounders, participants in the bottom quintile of 25(OH)D had similar cognitive function at baseline, as measured by a global cognitive score (mean difference: 0.09 (95% CI: −0.02, 0.19); p-trend: 0.18), and similar 2-year rates of cognitive decline (mean difference: −0.01 (95% CI: −0.09, 0.07), p-trend: 0.61) as those in the top 25(OH)D quintile. No significant associations were observed between baseline serum 25(OH)D concentration and 2-year change in individual cognitive test scores or change in executive function or memory domains. Conclusions: We observed no significant association between serum 25(OH)D and cognition in this cohort of Boston Area Puerto Ricans.
AB - Background: Vitamin D has been suggested as a protective factor for cognitive health, however results of prior studies have been mixed. To examine whether serum 25(OH)D concentration is related to cognition and cognitive decline in a study of Boston Area Puerto Ricans. Methods: We examined the association between serum 25(OH)D, cognitive function and cognitive decline in a longitudinal study of 967 Boston Area Puerto Rican adults. Results: In analyses adjusted for potential confounders, participants in the bottom quintile of 25(OH)D had similar cognitive function at baseline, as measured by a global cognitive score (mean difference: 0.09 (95% CI: −0.02, 0.19); p-trend: 0.18), and similar 2-year rates of cognitive decline (mean difference: −0.01 (95% CI: −0.09, 0.07), p-trend: 0.61) as those in the top 25(OH)D quintile. No significant associations were observed between baseline serum 25(OH)D concentration and 2-year change in individual cognitive test scores or change in executive function or memory domains. Conclusions: We observed no significant association between serum 25(OH)D and cognition in this cohort of Boston Area Puerto Ricans.
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U2 - 10.1080/1028415X.2018.1545291
DO - 10.1080/1028415X.2018.1545291
M3 - Article
C2 - 30843772
AN - SCOPUS:85062773071
SN - 1028-415X
VL - 23
SP - 688
EP - 695
JO - Nutritional Neuroscience
JF - Nutritional Neuroscience
IS - 9
ER -