Shortness of breath: Multiple causes of dyspnea in a woman with Ehlers-Danlos syndrome

Research output: Chapter in Book/Report/Conference proceedingChapter


Persons with Ehlers-Danlos syndromes or HSD may experience dyspnea (shortness of breath) due to multiple different causes. A comprehensive history and physical examination will narrow the list of potential diagnoses. Diagnostic tests usually involve a chest CT, ventilation/perfusion scan, spirometry, and pulmonary function tests. Pulmonologists, respiratory clinicians, and internists should include Ehlers-Danlos syndromes in their differential diagnosis when evaluating patients presenting with dyspnea. The reader should also consider rare but urgent causes of respiratory failure, including Guillain-Barre syndrome, acute intermittent porphyria, and ALS (amyotrophic lateral sclerosis). The reader is further directed to chapters on voice, fatigue, and apnea, gastroesophageal reflux, cervical instability, and scoliosis.

Original languageEnglish (US)
Title of host publicationSymptomatic
Subtitle of host publicationThe Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders
Number of pages8
ISBN (Electronic)9780323950824
ISBN (Print)9780323950831
StatePublished - Jan 1 2023

All Science Journal Classification (ASJC) codes

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology

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