Sickle Cell Disease

Gayle M. Smink

doi:10.1007/978-3-031-85765-2_55

Sickle Cell Disease

Gayle M. Smink

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Sickle cell disease is a rare inherited, lifelong blood disorder affecting an estimated 100,000 individuals in the United States (Centers for Disease Control and Prevention. Sickle Cell Disease (SCD). n.d. https://www.cdc.gov/ncbddd/sicklecell/index.html). Red blood cells contain hemoglobin which is responsible for carrying oxygen to the body. The genetic abnormality in sickle cell disease leads to a change in the shape of the red blood cell which results in vaso-occlusion and impaired blood flow. Vaso-occlusion leads to tissue damage and a resulting vasculopathy. Sickle cell disease can manifest with a variety of acute and chronic complications including pain, increased risk of infection, anemia, stroke, and others.

Original language	English (US)
Title of host publication	Clinical Considerations in School-based Health
Subtitle of host publication	An Evidence-Based Guide for Physicians, Advanced practice providers and School nurses
Publisher	Springer Science+Business Media
Pages	435-441
Number of pages	7
ISBN (Electronic)	9783031857652
ISBN (Print)	9783031857645
DOIs	https://doi.org/10.1007/978-3-031-85765-2_55
State	Published - Jan 1 2025

All Science Journal Classification (ASJC) codes

General Medicine

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10.1007/978-3-031-85765-2_55

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title = "Sickle Cell Disease",

abstract = "Sickle cell disease is a rare inherited, lifelong blood disorder affecting an estimated 100,000 individuals in the United States (Centers for Disease Control and Prevention. Sickle Cell Disease (SCD). n.d. https://www.cdc.gov/ncbddd/sicklecell/index.html). Red blood cells contain hemoglobin which is responsible for carrying oxygen to the body. The genetic abnormality in sickle cell disease leads to a change in the shape of the red blood cell which results in vaso-occlusion and impaired blood flow. Vaso-occlusion leads to tissue damage and a resulting vasculopathy. Sickle cell disease can manifest with a variety of acute and chronic complications including pain, increased risk of infection, anemia, stroke, and others.",

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N2 - Sickle cell disease is a rare inherited, lifelong blood disorder affecting an estimated 100,000 individuals in the United States (Centers for Disease Control and Prevention. Sickle Cell Disease (SCD). n.d. https://www.cdc.gov/ncbddd/sicklecell/index.html). Red blood cells contain hemoglobin which is responsible for carrying oxygen to the body. The genetic abnormality in sickle cell disease leads to a change in the shape of the red blood cell which results in vaso-occlusion and impaired blood flow. Vaso-occlusion leads to tissue damage and a resulting vasculopathy. Sickle cell disease can manifest with a variety of acute and chronic complications including pain, increased risk of infection, anemia, stroke, and others.

AB - Sickle cell disease is a rare inherited, lifelong blood disorder affecting an estimated 100,000 individuals in the United States (Centers for Disease Control and Prevention. Sickle Cell Disease (SCD). n.d. https://www.cdc.gov/ncbddd/sicklecell/index.html). Red blood cells contain hemoglobin which is responsible for carrying oxygen to the body. The genetic abnormality in sickle cell disease leads to a change in the shape of the red blood cell which results in vaso-occlusion and impaired blood flow. Vaso-occlusion leads to tissue damage and a resulting vasculopathy. Sickle cell disease can manifest with a variety of acute and chronic complications including pain, increased risk of infection, anemia, stroke, and others.

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BT - Clinical Considerations in School-based Health

PB - Springer Science+Business Media

ER -

Sickle Cell Disease

Abstract

All Science Journal Classification (ASJC) codes

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