SIMS-A precursor and partner to contemporary mass spectrometry

John C. Vickerman, Nicholas Winograd

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Significant events driving the development of SIMS over the last 50 years are reviewed. The discussion includes recollections of dynamic and static SIMS from the 1970s, of the emergence of TOF-SIMS during the 1980s and of the incorporation of cluster ion bombardment during most recent times. Advances in theoretical understanding of the sputtering phenomenon and of the ionization process that accompanied these advances are also included. Many early discoveries were focused upon the stimulated desorption of organic and bioorganic molecules, first via static SIMS and next via fast atom bombardment, that were important precursor experiments to modern day mass spectrometry. Today, submicron moleculespecific imaging and molecular depth profiling represent unique aspects of SIMS experiments. Developments that led to the optimization of these modalities are also emphasized in the review. In general, the characteristics of SIMS that make it a contemporary partner to modern day mass spectrometry are highlighted.

Original languageEnglish (US)
Pages (from-to)568-579
Number of pages12
JournalInternational Journal of Mass Spectrometry
Issue number1
StatePublished - 2015

All Science Journal Classification (ASJC) codes

  • Instrumentation
  • Condensed Matter Physics
  • Spectroscopy
  • Physical and Theoretical Chemistry


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