Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

Tian Tian; Heng Xiao; Xiaolian Zhang; Shuang Peng; Xiaoe Zhang; Shan Guo; Shaoru Wang; Songmei Liu; Xin Zhou; Craig Meyers; Xiang Zhou

doi:10.1039/c2cc36728a

Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

Tian Tian, Heng Xiao, Xiaolian Zhang, Shuang Peng, Xiaoe Zhang, Shan Guo, Shaoru Wang, Songmei Liu, Xin Zhou, Craig Meyers, Xiang Zhou

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43 Scopus citations

Abstract

We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.

Original language	English (US)
Pages (from-to)	75-77
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	1
DOIs	https://doi.org/10.1039/c2cc36728a
State	Published - 2013

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc36728a

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abstract = "We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.",

author = "Tian Tian and Heng Xiao and Xiaolian Zhang and Shuang Peng and Xiaoe Zhang and Shan Guo and Shaoru Wang and Songmei Liu and Xin Zhou and Craig Meyers and Xiang Zhou",

year = "2013",

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T1 - Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

AU - Tian, Tian

AU - Xiao, Heng

AU - Zhang, Xiaolian

AU - Peng, Shuang

AU - Zhang, Xiaoe

AU - Guo, Shan

AU - Wang, Shaoru

AU - Liu, Songmei

AU - Zhou, Xin

AU - Meyers, Craig

AU - Zhou, Xiang

PY - 2013

Y1 - 2013

N2 - We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.

AB - We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.

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DO - 10.1039/c2cc36728a

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JO - Chemical Communications

JF - Chemical Communications

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ER -

Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

Abstract

All Science Journal Classification (ASJC) codes

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