Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

  • Tian Tian
  • , Heng Xiao
  • , Xiaolian Zhang
  • , Shuang Peng
  • , Xiaoe Zhang
  • , Shan Guo
  • , Shaoru Wang
  • , Songmei Liu
  • , Xin Zhou
  • , Craig Meyers
  • , Xiang Zhou

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.

Original languageEnglish (US)
Pages (from-to)75-77
Number of pages3
JournalChemical Communications
Volume49
Issue number1
DOIs
StatePublished - 2013

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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