Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

Georgia Trakada; George P. Chrousos; Slobodanka Pejovic; Alexandros N. Vgontzas

doi:10.1016/j.jsmc.2007.04.003

Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

Georgia Trakada, George P. Chrousos, Slobodanka Pejovic, Alexandros N. Vgontzas

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive collapse of the upper airway during sleep leading to significant hypoxemia and recurrent arousals from sleep. OSA is associated with considerable morbidity and mortality. Four percent of adult men and two percent of adult women in general population random samples meet the current clinical and polysomnographic criteria for the diagnosis of sleep apnea. Obesity is the most important reversible risk factor for OSA. In this article, the authors review knowledge accumulated during the last 10 years about sleep apnea and its association with the stress system, inflammation, insulin resistance and visceral obesity.

Original language	English (US)
Pages (from-to)	251-261
Number of pages	11
Journal	Sleep Medicine Clinics
Volume	2
Issue number	2
DOIs	https://doi.org/10.1016/j.jsmc.2007.04.003
State	Published - Jun 2007

All Science Journal Classification (ASJC) codes

Neuropsychology and Physiological Psychology
Clinical Psychology
Clinical Neurology
Psychiatry and Mental health

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jsmc.2007.04.003

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title = "Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity",

abstract = "Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive collapse of the upper airway during sleep leading to significant hypoxemia and recurrent arousals from sleep. OSA is associated with considerable morbidity and mortality. Four percent of adult men and two percent of adult women in general population random samples meet the current clinical and polysomnographic criteria for the diagnosis of sleep apnea. Obesity is the most important reversible risk factor for OSA. In this article, the authors review knowledge accumulated during the last 10 years about sleep apnea and its association with the stress system, inflammation, insulin resistance and visceral obesity.",

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T1 - Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

AU - Trakada, Georgia

AU - Chrousos, George P.

AU - Pejovic, Slobodanka

AU - Vgontzas, Alexandros N.

PY - 2007/6

Y1 - 2007/6

N2 - Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive collapse of the upper airway during sleep leading to significant hypoxemia and recurrent arousals from sleep. OSA is associated with considerable morbidity and mortality. Four percent of adult men and two percent of adult women in general population random samples meet the current clinical and polysomnographic criteria for the diagnosis of sleep apnea. Obesity is the most important reversible risk factor for OSA. In this article, the authors review knowledge accumulated during the last 10 years about sleep apnea and its association with the stress system, inflammation, insulin resistance and visceral obesity.

AB - Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive collapse of the upper airway during sleep leading to significant hypoxemia and recurrent arousals from sleep. OSA is associated with considerable morbidity and mortality. Four percent of adult men and two percent of adult women in general population random samples meet the current clinical and polysomnographic criteria for the diagnosis of sleep apnea. Obesity is the most important reversible risk factor for OSA. In this article, the authors review knowledge accumulated during the last 10 years about sleep apnea and its association with the stress system, inflammation, insulin resistance and visceral obesity.

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JO - Sleep Medicine Clinics

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ER -

Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

Abstract

All Science Journal Classification (ASJC) codes

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