Abstract
This work presents the first sodium MRI functional renal study on a mouse model. The tissue sodium concentration was monitored during induced diuresis with furosemide. By using density-weighted chemical shift imaging (DWCSI) at high field strength a temporal resolution of less than 5 min for three dimensional (3D) data sets with high spatial resolution was achieved. A maximum increase of 20% in the cortex and a decrease of 45% of the original signal strength in the medulla were observed. These findings correspond well with experiments conducted on much larger rodent models.
Original language | English (US) |
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Pages (from-to) | 1067-1071 |
Number of pages | 5 |
Journal | Magnetic Resonance in Medicine |
Volume | 58 |
Issue number | 5 |
DOIs | |
State | Published - Nov 2007 |
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging