Soleus Muscle as a Surrogate for Health Status in Human Heart Failure

Daniel J. Green, Fausto A. Panizzolo, David G. Lloyd, Jonas Rubenson, Andrew J. Maiorana

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We propose the hypothesis that soleus muscle function may provide a surrogate measure of functional capacity in patients with heart failure. We summarize literature pertaining to skeletal muscle as a locus of fatigue and present our recent findings, using in vivo imaging in combination with biomechanical experimentation and modeling, to reveal novel structure-function relationships in chronic heart failure skeletal muscle and gait.

Original languageEnglish (US)
Pages (from-to)45-50
Number of pages6
JournalExercise and Sport Sciences Reviews
Issue number1
StatePublished - Jan 1 2016

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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