Why do some populations display a higher attack and mortality rate from the current coronavirus disease 2019 (COVID-19) pandemic than others? Are there geographic, environmental, behavioral, genetic, and comorbidity differences that influence spatial dynamics of COVID-19 transmission and outcomes? Where are the regional and country-level hotspots, and what drives those hotspots? These are some of the questions the current chapter strives to answer. The dynamics of transmission and consequences of COVID-19 are not homogeneous but instead have a geographical and spatial clustering. Population-level genetic, vaccination rates, health care disparities, SARS-CoV-2 variants, and meteorological factors are all underlying determinants of the disease dynamics globally, regionally, nationally, and locally. Disease surveillance frameworks to control, mitigate, and prevent the SARS- CoV-2 infections, particularly in low- and middle-income countries, are critical. Lastly, we highlight the spatial differences in the consequences of the pandemic focusing on behavioral and post-acute sequelae of SARS-CoV-2 infection.
|Original language||English (US)|
|Title of host publication||Frontiers of COVID-19|
|Subtitle of host publication||Scientific and Clinical Aspects of the Novel Coronavirus 2019|
|Publisher||Springer International Publishing|
|Number of pages||17|
|State||Published - Jan 1 2022|
All Science Journal Classification (ASJC) codes