Special Considerations of Anastomotic Leaks in Crohn's Disease

N. Nimalan A. Jeganathan, Walter A. Koltun

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Rates of anastomotic leak following intestinal resections in the setting of inflammatory bowel disease are significantly influenced by clinical characteristics. While the literature can be contradictory due to significant heterogeneity in the published data, several common themes appear to consistently arise. With respect to Crohn's disease, low serum albumin, preoperative abscess, reoperative abdominal surgery, and steroid use are associated with an increased risk of postoperative intra-abdominal septic complications. On the contrary, biologic therapy, immunomodulator use, and method of anastomosis appear not to confer increased anastomotic-related complications. Undoubtedly, a low rate of anastomotic leakage is inherent to procedures within colorectal surgery but diligent attention must be paid to identify, optimize, and, therefore, reduce known risks.

Original languageEnglish (US)
Pages (from-to)412-416
Number of pages5
JournalClinics in Colon and Rectal Surgery
Issue number6
StatePublished - Nov 1 2021

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology


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