Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia

TY - JOUR

T1 - Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia

AU - Barth, Brian M.

AU - Wang, Weiyuan

AU - Toran, Paul T.

AU - Fox, Todd E.

AU - Annageldiyev, Charyguly

AU - Ondrasik, Regina M.

AU - Keasey, Nicole R.

AU - Brown, Timothy J.

AU - Devine, Viola G.

AU - Sullivan, Emily C.

AU - Cote, Andrea L.

AU - Papakotsi, Vasiliki

AU - Tan, Su Fern

AU - Shanmugavelandy, Sriram S.

AU - Deering, Tye G.

AU - Needle, David B.

AU - Stern, Stephan T.

AU - Zhu, Junjia

AU - Liao, Jason

AU - Viny, Aaron D.

AU - Feith, David J.

AU - Levine, Ross L.

AU - Wang, Hong Gang

AU - Loughran, Thomas P.

AU - Sharma, Arati

AU - Kester, Mark

AU - Claxton, David F.

N1 - Funding Information: This work was funded in part by grants from the National Institutes of Health, National Cancer Institute (P01 CA171983 [M.K., T.P.L., and H.-G.W.] and K22 CA190674 [B.M.B.]), a Memorial Sloan Kettering Cancer Center Support Grant/Core Grant (P30 CA0087480) (R.L.L.), a National Institute of General Medical Sciences, University of New Hampshire COBRE Pilot Project Grant (P20 GM113131) (B.M.B.), the Bess Family Charitable Fund (T.P.L.), a generous anonymous donor (T.P.L.), the Penn State University Kiesendahl Family Endowed Leukemia Research Fund and the Kenneth Noel Memorial Fund (D.F.C.), and Pennsylvania Tobacco Settlement funds (M.K. and T.P.L.).

PY - 2019/9/10

Y1 - 2019/9/10

UR - https://www.scopus.com/pages/publications/85072193038

UR - https://www.scopus.com/pages/publications/85072193038#tab=citedBy

U2 - 10.1182/bloodadvances.2018021295

DO - 10.1182/bloodadvances.2018021295

M3 - Article

C2 - 31488436

AN - SCOPUS:85072193038

SN - 2473-9529

VL - 3

SP - 2598

EP - 2603

JO - Blood Advances

JF - Blood Advances

IS - 17

ER -