Stabilizing the C_H2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon

Immunology and Microbiology

• Fc Receptor 100%
• Immunoglobulin G 66%
• Binding Affinity 66%
• Monoclonal Antibody 66%
• Immunoglobulin G1 66%
• Protein Interaction 33%
• Crystal Structure 33%
• Wild Type 33%
• Immune Response 33%
• Receptor Binding 33%
• Glycan 33%
• Fucosylation 33%
• Immunoglobulin G1 Antibody 33%
• Melting Temperature 33%

Biochemistry, Genetics and Molecular Biology

• Sequon 100%
• Fc Receptor 60%
• Binding Affinity 40%
• Monoclonal Antibody 40%
• Immunoglobulin G 40%
• Fucose 40%
• Wild Type 20%
• Protein Interaction 20%
• Crystal Structure 20%
• Melting Temperature 20%
• Immune Response 20%
• Fucosylation 20%
• Polysaccharide 20%
• Receptor Binding 20%

Keyphrases

• CH2 Domain 100%
• IgG1 Fc 40%
• Fc Receptor Binding 20%
• Reverse Turns 20%
• Monoclonal IgG1 Antibody 20%
• Fc Portion 20%
• Antibody Fc 20%
• Aggregation Propensity 20%