Stereotactic Biopsy Considerations for Pineal Tumors

Brad E. Zacharia, Jeffrey N. Bruce

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Pineal region tumors represent 0.4% to 1.0% of intracranial tumors in American literature. Obtaining a tissue diagnosis is the cornerstone of the rational management of pineal lesions. The initial surgical decision involves choosing between a stereotactic biopsy and open microsurgical procedures. Open resection facilitates the maximal removal of tumor volume and has diagnostic accuracy and improved prognosis. Stereotactic biopsy is less invasive and has a lower risk of complications. A review of all major series reporting stereotactic biopsy for pineal region lesions reveals a mean diagnostic yield of 94%, with a morbidity of 1.3% and a mortality of 8.1%.

Original languageEnglish (US)
Pages (from-to)359-366
Number of pages8
JournalNeurosurgery clinics of North America
Issue number3
StatePublished - Jul 2011

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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