Abstract
Steam-in-place (SIP) sterilization was carried out on 9.4 cm long tubes with inside diameters varying from 0.39 to 1.6 cm. Tubes were orientated vertically and B. stearothermophilus spores used to monitor sterilization. Time to achieve sterilization was strongly dependent on tube diameter with the larger diameter tube requiring less than eighteen minutes to sterilize, whereas the smallest tube could not be sterilized in two hours. A two-dimensional finite element model was developed and predicted steam penetration up the tubes to be buoyancy driven with larger diameter tubes achieving saturated steam conditions faster than smaller tubes. Cellular flow patterns were predicted with tube diameter determining cellular size and thus rate of steam penetration up the tube.
| Original language | English (US) |
|---|---|
| Title of host publication | 1992 Advances in Bioengineering |
| Publisher | Publ by ASME |
| Pages | 457-460 |
| Number of pages | 4 |
| Volume | 22 |
| ISBN (Print) | 0791811166 |
| State | Published - 1992 |
| Event | Winter Annual Meeting of the American Society of Mechanical Engineers - Anaheim, CA, USA Duration: Nov 8 1992 → Nov 13 1992 |
Other
| Other | Winter Annual Meeting of the American Society of Mechanical Engineers |
|---|---|
| City | Anaheim, CA, USA |
| Period | 11/8/92 → 11/13/92 |
All Science Journal Classification (ASJC) codes
- General Engineering