Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

T. M. Zydowsky; L. F. Courtney; V. Frasca; R. G. Matthews; L. D. Yuen; H. Shimizu; K. Kobayashi; S. J. Benkovic; H. G. Floss

doi:10.1021/ja00271a081

Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

T. M. Zydowsky, L. F. Courtney, V. Frasca, R. G. Matthews, L. D. Yuen, H. Shimizu, K. Kobayashi, S. J. Benkovic, H. G. Floss

Chemistry

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65 Scopus citations

Abstract

The last step in the biosynthesis of methionine involves transfer of the methyl group of TV5-methyltetrahydrofolate (5-CH₃-H₄-folate) or its polyglutamate analogue to the sulfur of homocysteine.

Original language	English (US)
Pages (from-to)	3152-3153
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	108
Issue number	11
DOIs	https://doi.org/10.1021/ja00271a081
State	Published - 1986

All Science Journal Classification (ASJC) codes

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja00271a081

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title = "Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B",

abstract = "The last step in the biosynthesis of methionine involves transfer of the methyl group of TV5-methyltetrahydrofolate (5-CH3-H4-folate) or its polyglutamate analogue to the sulfur of homocysteine.",

author = "Zydowsky, {T. M.} and Courtney, {L. F.} and V. Frasca and Matthews, {R. G.} and Yuen, {L. D.} and H. Shimizu and K. Kobayashi and Benkovic, {S. J.} and Floss, {H. G.}",

year = "1986",

doi = "10.1021/ja00271a081",

language = "English (US)",

volume = "108",

pages = "3152--3153",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

AU - Zydowsky, T. M.

AU - Courtney, L. F.

AU - Frasca, V.

AU - Matthews, R. G.

AU - Yuen, L. D.

AU - Shimizu, H.

AU - Kobayashi, K.

AU - Benkovic, S. J.

AU - Floss, H. G.

PY - 1986

Y1 - 1986

N2 - The last step in the biosynthesis of methionine involves transfer of the methyl group of TV5-methyltetrahydrofolate (5-CH3-H4-folate) or its polyglutamate analogue to the sulfur of homocysteine.

AB - The last step in the biosynthesis of methionine involves transfer of the methyl group of TV5-methyltetrahydrofolate (5-CH3-H4-folate) or its polyglutamate analogue to the sulfur of homocysteine.

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U2 - 10.1021/ja00271a081

DO - 10.1021/ja00271a081

M3 - Article

AN - SCOPUS:33845376143

SN - 0002-7863

VL - 108

SP - 3152

EP - 3153

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 11

ER -

Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

Abstract

All Science Journal Classification (ASJC) codes

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