TY - JOUR
T1 - Stimulant medications decrease energy expenditure and physical activity in children with attention-deficit/hyperactivity disorder
AU - Butte, N. F.
AU - Treuth, M. S.
AU - Voigt, R. G.
AU - Llorente, A. M.
AU - Heird, W. C.
N1 - Funding Information:
Supported in part with federal funds from the US Department of Agriculture/Agricultural Research Service USDA/ARS under Cooperative Agreement number 58-6250-6-001 and by a grant from the Martek Biosciences Corporation.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1999
Y1 - 1999
N2 - Objective: To determine the effect of stimulant medications used to treat children with attention-deficit/hyperactivity disorder (AD/HD) on energy expenditure, fuel utilization, and physical activity. Study design: Energy expenditure and physical activity were measured, respectively, by room respiration calorimetry and microwave motion detectors in 31 children with AD/HD (26 boys and 5 girls; ages 6 to 12 years) both while they were receiving their prescribed stimulant medication and after the medication had been discontinued for at least 24 hours. Fuel utilization was calculated from calorimetry data. Results: Total and awake energy expenditure including energy expended while doing schoolwork, riding a stationary bicycle, resting, and watching a movie were from 4% to 8% lower when the children were receiving their prescribed stimulant medication. Total and awake activity were also lower while they were receiving medication (16% to 22%) and accounted for the lower rates of energy expenditure. Sleeping metabolic rate, basal metabolic rate, and fuel utilization were unaffected by medication. Conclusions: Stimulant medications decrease physical activity, and hence, decrease the activity component of total daily energy expenditure in children with AD/HD.
AB - Objective: To determine the effect of stimulant medications used to treat children with attention-deficit/hyperactivity disorder (AD/HD) on energy expenditure, fuel utilization, and physical activity. Study design: Energy expenditure and physical activity were measured, respectively, by room respiration calorimetry and microwave motion detectors in 31 children with AD/HD (26 boys and 5 girls; ages 6 to 12 years) both while they were receiving their prescribed stimulant medication and after the medication had been discontinued for at least 24 hours. Fuel utilization was calculated from calorimetry data. Results: Total and awake energy expenditure including energy expended while doing schoolwork, riding a stationary bicycle, resting, and watching a movie were from 4% to 8% lower when the children were receiving their prescribed stimulant medication. Total and awake activity were also lower while they were receiving medication (16% to 22%) and accounted for the lower rates of energy expenditure. Sleeping metabolic rate, basal metabolic rate, and fuel utilization were unaffected by medication. Conclusions: Stimulant medications decrease physical activity, and hence, decrease the activity component of total daily energy expenditure in children with AD/HD.
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U2 - 10.1016/S0022-3476(99)70023-5
DO - 10.1016/S0022-3476(99)70023-5
M3 - Article
C2 - 10431115
AN - SCOPUS:0033510654
SN - 0022-3476
VL - 135
SP - 203
EP - 207
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 2 I
ER -