Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction

Alexandr M. Degtyarenko; Marc Kaufman

doi:10.1016/S0006-8993(00)02738-4

Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction

Alexandr M. Degtyarenko
, Marc Kaufman

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. Copyright (C) 2000 Elsevier Science B.V.

Original language	English (US)
Pages (from-to)	178-182
Number of pages	5
Journal	Brain research
Volume	880
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(00)02738-4
State	Published - Oct 13 2000

All Science Journal Classification (ASJC) codes

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(00)02738-4

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title = "Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction",

abstract = "We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. Copyright (C) 2000 Elsevier Science B.V.",

author = "Degtyarenko, \{Alexandr M.\} and Marc Kaufman",

note = "Funding Information: This work was supported by NIH Grant HL 30710. We thank Eileen English for typing the manuscript. ",

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AU - Degtyarenko, Alexandr M.

AU - Kaufman, Marc

N1 - Funding Information: This work was supported by NIH Grant HL 30710. We thank Eileen English for typing the manuscript.

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Y1 - 2000/10/13

N2 - We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. Copyright (C) 2000 Elsevier Science B.V.

AB - We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. Copyright (C) 2000 Elsevier Science B.V.

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JF - Brain research

IS - 1-2

ER -

Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction

Abstract

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