Stochastic sensors inspired by biology

Hagan Bayley; Paul S. Cremer

doi:10.1038/35093038

Stochastic sensors inspired by biology

Hagan Bayley, Paul S. Cremer

Research output: Contribution to journal › Review article › peer-review

979 Scopus citations

Abstract

Sensory systems use a variety of membrane-bound receptors, including responsive ion channels, to discriminate between a multitude of stimuli. Here we describe how engineered membrane pores can be used to make rapid and sensitive biosensors with potential applications that range from the detection of biological warfare agents to pharmaceutical screening. Notably, use of the engineered pores in stochastic sensing, a single-molecule detection technology, reveals the identity of an analyte as well as its concentration.

Original language	English (US)
Pages (from-to)	226-230
Number of pages	5
Journal	Nature
Volume	413
Issue number	6852
DOIs	https://doi.org/10.1038/35093038
State	Published - Sep 13 2001

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Stochastic sensors inspired by biology

Abstract

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