TY - JOUR
T1 - Stress-Related Disorders of Family Members of Patients Admitted to the Intensive Care Unit with COVID-19
AU - Amass, Timothy
AU - Van Scoy, Lauren Jodi
AU - Hua, May
AU - Ambler, Melanie
AU - Armstrong, Priscilla
AU - Baldwin, Matthew R.
AU - Bernacki, Rachelle
AU - Burhani, Mansoor D.
AU - Chiurco, Jennifer
AU - Cooper, Zara
AU - Cruse, Hope
AU - Csikesz, Nicholas
AU - Engelberg, Ruth A.
AU - Fonseca, Laura D.
AU - Halvorson, Karin
AU - Hammer, Rachel
AU - Heywood, Joanna
AU - Duda, Sarah Hochendoner
AU - Huang, Jin
AU - Jin, Ying
AU - Johnson, Laura
AU - Tabata-Kelly, Masami
AU - Kerr, Emma
AU - Lane, Trevor
AU - Lee, Melissa
AU - Likosky, Keely
AU - McGuirl, Donald
AU - Milinic, Tijana
AU - Moss, Marc
AU - Nielsen, Elizabeth
AU - Peterson, Ryan
AU - Puckey, Sara J.
AU - Rea, Olivia
AU - Rhoads, Sarah
AU - Sheu, Christina
AU - Tong, Wendy
AU - Witt, Pamela D.
AU - Wykowski, James
AU - Yu, Stephanie
AU - Stapleton, Renee D.
AU - Curtis, J. Randall
N1 - Publisher Copyright:
© 2022 American Medical Association. All rights reserved.
PY - 2022/6
Y1 - 2022/6
N2 - Importance: The psychological symptoms associated with having a family member admitted to the intensive care unit (ICU) during the COVID-19 pandemic are not well defined. Objective: To examine the prevalence of symptoms of stress-related disorders, primarily posttraumatic stress disorder (PTSD), in family members of patients admitted to the ICU with COVID-19 approximately 90 days after admission. Design, Setting, and Participants: This prospective, multisite, mixed-methods observational cohort study assessed 330 family members of patients admitted to the ICU (except in New York City, which had a random sample of 25% of all admitted patients per month) between February 1 and July 31, 2020, at 8 academic-affiliated and 4 community-based hospitals in 5 US states. Exposure: Having a family member in the ICU with COVID-19. Main Outcomes and Measures: Symptoms of PTSD at 3 months, as defined by a score of 10 or higher on the Impact of Events Scale 6 (IES-6). Results: A total of 330 participants (mean [SD] age, 51.2 [15.1] years; 228 [69.1%] women; 150 [52.8%] White; 92 [29.8%] Hispanic) were surveyed at the 3-month time point. Most individuals were the patients' child (129 [40.6%]) or spouse or partner (81 [25.5%]). The mean (SD) IES-6 score at 3 months was 11.9 (6.1), with 201 of 316 respondents (63.6%) having scores of 10 or higher, indicating significant symptoms of PTSD. Female participants had an adjusted mean IES-6 score of 2.6 points higher (95% CI, 1.4-3.8; P <.001) than male participants, whereas Hispanic participants scored a mean of 2.7 points higher compared with non-Hispanic participants (95% CI, 1.0-4.3; P =.002). Those with graduate school experience had an adjusted mean score of 3.3 points lower (95% CI, 1.5-5.1; P <.001) compared with those with up to a high school degree or equivalent. Qualitative analyses found no substantive differences in the emotional or communication-related experiences between those with high vs low PTSD scores, but those with higher scores exhibited more distrust of practitioners. Conclusions and Relevance: In this cohort study, symptoms of PTSD among family members of ICU patients with COVID-19 were high. Hispanic ethnicity and female gender were associated with higher symptoms. Those with higher scores reported more distrust of practitioners..
AB - Importance: The psychological symptoms associated with having a family member admitted to the intensive care unit (ICU) during the COVID-19 pandemic are not well defined. Objective: To examine the prevalence of symptoms of stress-related disorders, primarily posttraumatic stress disorder (PTSD), in family members of patients admitted to the ICU with COVID-19 approximately 90 days after admission. Design, Setting, and Participants: This prospective, multisite, mixed-methods observational cohort study assessed 330 family members of patients admitted to the ICU (except in New York City, which had a random sample of 25% of all admitted patients per month) between February 1 and July 31, 2020, at 8 academic-affiliated and 4 community-based hospitals in 5 US states. Exposure: Having a family member in the ICU with COVID-19. Main Outcomes and Measures: Symptoms of PTSD at 3 months, as defined by a score of 10 or higher on the Impact of Events Scale 6 (IES-6). Results: A total of 330 participants (mean [SD] age, 51.2 [15.1] years; 228 [69.1%] women; 150 [52.8%] White; 92 [29.8%] Hispanic) were surveyed at the 3-month time point. Most individuals were the patients' child (129 [40.6%]) or spouse or partner (81 [25.5%]). The mean (SD) IES-6 score at 3 months was 11.9 (6.1), with 201 of 316 respondents (63.6%) having scores of 10 or higher, indicating significant symptoms of PTSD. Female participants had an adjusted mean IES-6 score of 2.6 points higher (95% CI, 1.4-3.8; P <.001) than male participants, whereas Hispanic participants scored a mean of 2.7 points higher compared with non-Hispanic participants (95% CI, 1.0-4.3; P =.002). Those with graduate school experience had an adjusted mean score of 3.3 points lower (95% CI, 1.5-5.1; P <.001) compared with those with up to a high school degree or equivalent. Qualitative analyses found no substantive differences in the emotional or communication-related experiences between those with high vs low PTSD scores, but those with higher scores exhibited more distrust of practitioners. Conclusions and Relevance: In this cohort study, symptoms of PTSD among family members of ICU patients with COVID-19 were high. Hispanic ethnicity and female gender were associated with higher symptoms. Those with higher scores reported more distrust of practitioners..
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U2 - 10.1001/jamainternmed.2022.1118
DO - 10.1001/jamainternmed.2022.1118
M3 - Article
C2 - 35467698
AN - SCOPUS:85129280924
SN - 2168-6106
VL - 182
SP - 624
EP - 633
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
IS - 6
ER -