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Structural and thermodynamic effects of post-translational modifications in mutant and wild type Cu, Zn superoxide dismutase
Elizabeth Anne Proctor
, Feng Ding
, Nikolay Dokholyan
Department of Neurosurgery
Biomedical Engineering
Cancer Institute, Next-Generation Therapies
Penn State Cancer Institute
Center for Neural Engineering
Engineering Science and Mechanics
Penn State Neuroscience Institute
Penn State Clinical and Translational Science Institute (CTSI)
Center for Cannabis and Natural Product Pharmaceuticals (CCNPP)
Department of Neuroscience and Experimental Therapeutics
Research output
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Contribution to journal
›
Article
›
peer-review
41
Scopus citations
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Dive into the research topics of 'Structural and thermodynamic effects of post-translational modifications in mutant and wild type Cu, Zn superoxide dismutase'. Together they form a unique fingerprint.
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Keyphrases
Post-translational Modification
100%
Superoxide Dismutase 1 (SOD1)
100%
Structural Effect
100%
Thermodynamic Effect
100%
Zn-superoxide Dismutase
100%
Glutathionylation
42%
Intermediate State
28%
Amyotrophic Lateral Sclerosis
28%
Dimer Dissociation
28%
Environmental Factors
14%
Healthy Individuals
14%
Phosphorylation
14%
Conformational Change
14%
Oxidative Stress
14%
Disease Progression
14%
Dissociation
14%
Human Body
14%
Dimer Interface
14%
Loosening
14%
Interface Interaction
14%
Sporadic Cases
14%
SOD1 Aggregation
14%
Biochemistry, Genetics and Molecular Biology
Posttranslational Modification
100%
Wild Type
100%
Superoxide Dismutase
100%
SOD1
100%
Glutathionylation
37%
Conformational Change
12%
Oxidative Stress
12%