Structural basis for μ-opioid receptor binding and activation

Keyphrases

• Analgesic 33%
• Binder 33%
• Binding Residues 33%
• Biochemical Assay 33%
• Cell Signaling 33%
• Conformational Flexibility 33%
• Functional Assay 33%
• G Protein 33%
• High Efficacy 33%
• High Potency 33%
• Ligand-dependent 33%
• Molecular Dynamics Simulation 33%
• MOR-1 100%
• Novel Analgesics 33%
• Opioid Receptor Activation 100%
• Opioid Receptor Binding 100%
• Opioid Receptors 33%
• Opioids 33%
• Protein Complex 33%
• Radioligand Binding Assay 33%
• Site-directed mutagenesis 33%
• Structural Mechanism 33%
• Third Intracellular Loop 33%

Biochemistry, Genetics and Molecular Biology

• Opioid Receptor 100%
• Protein Complexes 50%
• Radioligand 50%
• Receptor Binding 100%
• Signal Transduction 50%
• Site-Directed Mutagenesis 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Analgesic Agent 100%
• Guanine Nucleotide Binding Protein 50%
• Nalmefene 50%
• Opiate Receptor 100%
• Radioligand 50%
• Site-Directed Mutagenesis 50%