Study on killing effects of purine nucleoside phosphorylase/fludarabine (PNP/fludarabine) suicide gene system on human hepatocellular carcinoma cell line BEL7402 in vitro

Keyphrases

• Fludarabine 100%
• Killing Effect 100%
• Human Hepatocellular Carcinoma Cell Line 100%
• Purine nucleoside Phosphorylase 100%
• Bystander Effect 20%
• Quantitative PCR 13%
• Prodrug 13%
• Northern Blotting 13%
• Cytotoxic Effect 13%
• Colorimetric Method 6%
• Incubation 6%
• Genomic DNA (gDNA) 6%
• Gene Therapy 6%
• Cancer Cells 6%
• Polymerase Chain Reaction 6%
• Tumor Cells 6%
• Apoptotic Effect 6%
• Gene-gene 6%
• Glycine 6%
• Linker 6%
• Apoptosis Induction 6%
• Effects on Humans 6%
• Escherichia Coli K-12 6%
• Toxic Metabolites 6%
• Death Rate 6%
• Detection Device 6%
• G418 6%
• Apoptosis Analysis 6%
• Annexin V-FITC 6%
• Eukaryotic Expression Vector 6%
• Suicide Gene 6%
• Therapeutic Area 6%

Pharmacology, Toxicology and Pharmaceutical Science

• Liver Cell Carcinoma 100%
• Fludarabine 100%
• Purine Nucleoside Phosphorylase 100%
• Prodrug 20%
• RNA Directed DNA Polymerase 13%
• Malignant Neoplasm 6%
• Neoplasm 6%
• Fluorescein Isothiocyanate 6%
• Lipofectamine 6%
• Calorimetry 6%
• Escherichia Coli K 12 6%
• Lipocortin 5 6%
• Genomic DNA 6%
• Toxin 6%
• Tetrazolium 6%

Biochemistry, Genetics and Molecular Biology

• Fludarabine 100%
• Purine Nucleoside Phosphorylase 100%
• Bystander Effect 20%
• Programmed Cell Death 20%
• Northern Blotting 13%
• Low Drug Dose 13%
• Cytotoxicity 13%
• Reverse Transcription Polymerase Chain Reaction 13%
• Calorimetry 6%
• Metabolite 6%
• Enzyme 6%
• Cancer Cell 6%
• Gene Therapy 6%
• Lipofectamine 6%
• Eukaryotic Expression Vector 6%
• Escherichia Coli K 12 6%
• G418 6%
• Lipocortin 6%