Study to investigate the potential of probiotics in children attending school

D. Merenstein, J. Gonzalez, A. G. Young, R. F. Roberts, M. E. Sanders, S. Petterson

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Background/Objectives:To determine if consumption of yogurt containing a high dose of probiotic (1 × 1010 colony-forming unit per 100 ml), Bifidobacterium animalis subsp. lactis (B. lactis), decreases absences in children 2-4 years attending daycare/school centers.Subjects/Methods:We conducted a double-blinded, randomized, placebo-controlled, allocation concealment clinical trial in the Washington, DC area. Our active intervention was a strawberry yogurt-based drink supplemented with B. lactis BB-12. The placebo was indistinguishable from the active drink, differing only in absence of the probiotic BB-12. Results: A total of 172 children between the ages of 2 and 4 from the Washington, DC area were enrolled. The primary outcome, missed days of school because of illness per 100 days, was similar in both the active (2.54 days absent/100 school days) and control groups (2.42 days absent/100 school days) (P=0.873).Conclusions:The probiotic-containing yogurt-based beverage studied did not decrease absences because of illnesses in daycare/school for healthy children ages 2-4 years.

Original languageEnglish (US)
Pages (from-to)447-453
Number of pages7
JournalEuropean Journal of Clinical Nutrition
Issue number4
StatePublished - Apr 2011

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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