Submicrometer metallic barcodes

S. R. Nicewarner-Peña; R. G. Freeman; B. D. Reiss; L. He; D. J. Peña; I. D. Walton; R. Cromer; C. D. Keating; M. J. Natan

doi:10.1126/science.294.5540.137

Submicrometer metallic barcodes

S. R. Nicewarner-Peña, R. G. Freeman, B. D. Reiss, L. He, D. J. Peña, I. D. Walton, R. Cromer, C. D. Keating, M. J. Natan

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1282 Scopus citations

Abstract

We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.

Original language	English (US)
Pages (from-to)	137-141
Number of pages	5
Journal	Science
Volume	294
Issue number	5540
DOIs	https://doi.org/10.1126/science.294.5540.137
State	Published - Oct 5 2001

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10.1126/science.294.5540.137

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title = "Submicrometer metallic barcodes",

abstract = "We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.",

author = "Nicewarner-Pe{\~n}a, {S. R.} and Freeman, {R. G.} and Reiss, {B. D.} and L. He and Pe{\~n}a, {D. J.} and Walton, {I. D.} and R. Cromer and Keating, {C. D.} and Natan, {M. J.}",

year = "2001",

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doi = "10.1126/science.294.5540.137",

language = "English (US)",

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T1 - Submicrometer metallic barcodes

AU - Nicewarner-Peña, S. R.

AU - Freeman, R. G.

AU - Reiss, B. D.

AU - He, L.

AU - Peña, D. J.

AU - Walton, I. D.

AU - Cromer, R.

AU - Keating, C. D.

AU - Natan, M. J.

PY - 2001/10/5

Y1 - 2001/10/5

N2 - We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.

AB - We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.

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DO - 10.1126/science.294.5540.137

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VL - 294

SP - 137

EP - 141

JO - Science

JF - Science

IS - 5540

ER -

Submicrometer metallic barcodes

Abstract

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