Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report

Stephanie J. Estes; Donna C. Laky; Linda M. Hoover; Scott E. Smith; Jay S. Schinfeld; Stephen G. Somkuti

Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report

Stephanie J. Estes, Donna C. Laky, Linda M. Hoover, Scott E. Smith, Jay S. Schinfeld, Stephen G. Somkuti

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Twice-frozen, thawed embryos may have utilization in in vitro fertilization (IVF) cycles. CASE: A 37-year-old woman with endometriosis and infertility returned five years after a fresh IVF cycle. Seven cryopreserved embryos (2 pronuclear [pn] and cleaved) were thawed, and five developed to the blastocyst stage. One blastocyst was transferred, and the remaining four were recryopreserved. This transfer did not result in pregnancy. The remaining four blastocysts were thawed, and two were transferred resulting in a live, singleton delivery. CONCLUSION: Pregnancy can result from cryopreserved 2-pn and cleaved embryos cultured to blastocysts, refrozen and then transferred at the blastocyst stage.

Original language	English (US)
Pages (from-to)	46-48
Number of pages	3
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	48
Issue number	1
State	Published - Jan 1 2003

All Science Journal Classification (ASJC) codes

Reproductive Medicine
Obstetrics and Gynecology

Cite this

@article{bad53c4e510a47eb96bbf9d08f436658,

title = "Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report",

abstract = "BACKGROUND: Twice-frozen, thawed embryos may have utilization in in vitro fertilization (IVF) cycles. CASE: A 37-year-old woman with endometriosis and infertility returned five years after a fresh IVF cycle. Seven cryopreserved embryos (2 pronuclear [pn] and cleaved) were thawed, and five developed to the blastocyst stage. One blastocyst was transferred, and the remaining four were recryopreserved. This transfer did not result in pregnancy. The remaining four blastocysts were thawed, and two were transferred resulting in a live, singleton delivery. CONCLUSION: Pregnancy can result from cryopreserved 2-pn and cleaved embryos cultured to blastocysts, refrozen and then transferred at the blastocyst stage.",

author = "Estes, {Stephanie J.} and Laky, {Donna C.} and Hoover, {Linda M.} and Smith, {Scott E.} and Schinfeld, {Jay S.} and Somkuti, {Stephen G.}",

year = "2003",

month = jan,

day = "1",

language = "English (US)",

volume = "48",

pages = "46--48",

journal = "Journal of Reproductive Medicine for the Obstetrician and Gynecologist",

issn = "0024-7758",

publisher = "Journal of Reproductive Medicine, Inc.",

number = "1",

}

Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report. / Estes, Stephanie J.; Laky, Donna C.; Hoover, Linda M. et al.
In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 48, No. 1, 01.01.2003, p. 46-48.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred

T2 - A case report

AU - Estes, Stephanie J.

AU - Laky, Donna C.

AU - Hoover, Linda M.

AU - Smith, Scott E.

AU - Schinfeld, Jay S.

AU - Somkuti, Stephen G.

PY - 2003/1/1

Y1 - 2003/1/1

N2 - BACKGROUND: Twice-frozen, thawed embryos may have utilization in in vitro fertilization (IVF) cycles. CASE: A 37-year-old woman with endometriosis and infertility returned five years after a fresh IVF cycle. Seven cryopreserved embryos (2 pronuclear [pn] and cleaved) were thawed, and five developed to the blastocyst stage. One blastocyst was transferred, and the remaining four were recryopreserved. This transfer did not result in pregnancy. The remaining four blastocysts were thawed, and two were transferred resulting in a live, singleton delivery. CONCLUSION: Pregnancy can result from cryopreserved 2-pn and cleaved embryos cultured to blastocysts, refrozen and then transferred at the blastocyst stage.

AB - BACKGROUND: Twice-frozen, thawed embryos may have utilization in in vitro fertilization (IVF) cycles. CASE: A 37-year-old woman with endometriosis and infertility returned five years after a fresh IVF cycle. Seven cryopreserved embryos (2 pronuclear [pn] and cleaved) were thawed, and five developed to the blastocyst stage. One blastocyst was transferred, and the remaining four were recryopreserved. This transfer did not result in pregnancy. The remaining four blastocysts were thawed, and two were transferred resulting in a live, singleton delivery. CONCLUSION: Pregnancy can result from cryopreserved 2-pn and cleaved embryos cultured to blastocysts, refrozen and then transferred at the blastocyst stage.

UR - http://www.scopus.com/inward/record.url?scp=0037244193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037244193&partnerID=8YFLogxK

M3 - Article

C2 - 12611095

AN - SCOPUS:0037244193

SN - 0024-7758

VL - 48

SP - 46

EP - 48

JO - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

JF - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

IS - 1

ER -

Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this