TY - JOUR
T1 - Successful Treatment of Narcolepsy with Propranolol
T2 - A Case Report
AU - Kales, Anthony
AU - Soldatos, Constantin R.
AU - Cadieux, Roger
AU - Tan, Tjiauw Ling
PY - 1979/10
Y1 - 1979/10
N2 - A patient with severe narcolepsy and cataplexy had been treated with a high dosage of methylphenidate hydrochloride, but the drug was not effective. To relieve the patient's cardiac arrhythmia, which was assumed to be secondary to drug therapy, we withdrew methylphenidate therapy and started propranolol hydrochloride therapy. When the dosage of propranolol was increased to a level consistent with maximum β-adrenergic receptor blockade, the attacks were eliminated.
AB - A patient with severe narcolepsy and cataplexy had been treated with a high dosage of methylphenidate hydrochloride, but the drug was not effective. To relieve the patient's cardiac arrhythmia, which was assumed to be secondary to drug therapy, we withdrew methylphenidate therapy and started propranolol hydrochloride therapy. When the dosage of propranolol was increased to a level consistent with maximum β-adrenergic receptor blockade, the attacks were eliminated.
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U2 - 10.1001/archneur.1979.00500460084015
DO - 10.1001/archneur.1979.00500460084015
M3 - Article
C2 - 485897
AN - SCOPUS:0018308823
SN - 0003-9942
VL - 36
SP - 650
EP - 651
JO - Archives of Neurology
JF - Archives of Neurology
IS - 10
ER -