Surgical left ventricular remodeling procedures

Jonathan F. Wenk, Choon Sik Jhun, Kay Sun, Mark B. Ratcliffe, Julius M. Guccione

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Perhaps the most straightforward clinical application of validated regional ventricular mechanics models for diseased hearts is the simulation of a novel surgical procedure or medical device for treating heart failure or ischemic cardiomyopathy. In each study our cardiac biomechanics laboratory uses one of two different approaches: (1) an axisymmetric truncated ellipsoidal model with left ventricular (LV) cavity and wall volumes typical of the failing human heart or animal model of heart failure to determine efficacy of the surgical procedure or device; or (2) an animal-or patient-specific fully 3-D model of the infarcted LV created using echocardiography or MRI to optimize the design of the surgical procedure or device. This chapter is concerned with brief descriptions of the studies from our laboratory that provide the best examples of these two approaches.

Original languageEnglish (US)
Title of host publicationComputational Cardiovascular Mechanics
Subtitle of host publicationModeling and Applications in Heart Failure
PublisherSpringer US
Number of pages14
ISBN (Print)9781441907295
StatePublished - Dec 1 2010

All Science Journal Classification (ASJC) codes

  • General Engineering


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