Surgical Options for Neoplasia Complicating Crohn’s Disease of the Large Intestine

Jeffrey S. Scow; Amit Merchea

doi:10.1007/978-3-030-16755-4_16

Surgical Options for Neoplasia Complicating Crohn’s Disease of the Large Intestine

Jeffrey S. Scow
, Amit Merchea

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Individuals with Crohn’s disease (CD) of the large intestine develop colorectal cancer at an increased rate compared to the general population. The exact magnitude of increased risk is unknown. The prevalence of dysplasia at 25 years has been reported to range between 0.5% to 25% and the risk for colorectal cancer may be six-fold that of the general population. Colorectal cancer in patients with inflammatory bowel disease (IBD) appears to develop via a pathway that deviates from the well characterized adenoma-carcinoma sequence of sporadic colorectal cancer and may progress rapidly, skipping steps seen with sporadic colorectal cancer.

Original language	English (US)
Title of host publication	Mastery of IBD Surgery
Publisher	Springer International Publishing
Pages	151-160
Number of pages	10
ISBN (Electronic)	9783030167554
ISBN (Print)	9783030167547
DOIs	https://doi.org/10.1007/978-3-030-16755-4_16
State	Published - Jan 1 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General Medicine

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10.1007/978-3-030-16755-4_16

Cite this

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abstract = "Individuals with Crohn{\textquoteright}s disease (CD) of the large intestine develop colorectal cancer at an increased rate compared to the general population. The exact magnitude of increased risk is unknown. The prevalence of dysplasia at 25 years has been reported to range between 0.5\% to 25\% and the risk for colorectal cancer may be six-fold that of the general population. Colorectal cancer in patients with inflammatory bowel disease (IBD) appears to develop via a pathway that deviates from the well characterized adenoma-carcinoma sequence of sporadic colorectal cancer and may progress rapidly, skipping steps seen with sporadic colorectal cancer.",

author = "Scow, \{Jeffrey S.\} and Amit Merchea",

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N2 - Individuals with Crohn’s disease (CD) of the large intestine develop colorectal cancer at an increased rate compared to the general population. The exact magnitude of increased risk is unknown. The prevalence of dysplasia at 25 years has been reported to range between 0.5% to 25% and the risk for colorectal cancer may be six-fold that of the general population. Colorectal cancer in patients with inflammatory bowel disease (IBD) appears to develop via a pathway that deviates from the well characterized adenoma-carcinoma sequence of sporadic colorectal cancer and may progress rapidly, skipping steps seen with sporadic colorectal cancer.

AB - Individuals with Crohn’s disease (CD) of the large intestine develop colorectal cancer at an increased rate compared to the general population. The exact magnitude of increased risk is unknown. The prevalence of dysplasia at 25 years has been reported to range between 0.5% to 25% and the risk for colorectal cancer may be six-fold that of the general population. Colorectal cancer in patients with inflammatory bowel disease (IBD) appears to develop via a pathway that deviates from the well characterized adenoma-carcinoma sequence of sporadic colorectal cancer and may progress rapidly, skipping steps seen with sporadic colorectal cancer.

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ER -

Surgical Options for Neoplasia Complicating Crohn’s Disease of the Large Intestine

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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