TY - JOUR
T1 - Syntheses of Nitrogen-Containing Heterocycles via Palladium-Catalyzed Intramolecular Dehydrogenative C-H Amination
AU - Nack, William A.
AU - Chen, Gong
N1 - Publisher Copyright:
© 2015 Georg Thieme Verlag Stuttgart, New York -Synlett.
PY - 2015/6/16
Y1 - 2015/6/16
N2 - This article traces the development of catalytic, intramolecular dehydrogenative C-H amination (IDCA) reactions. Over the last 10 years, effective syntheses of carbazoles, indolines and oxindoles via palladium-catalyzed sp2 intramolecular dehydrogenative C-H amination reactions have been realized. While the corresponding amination reactions of sp3 C-H bonds are more challenging, syntheses of pyrrolidines, azetidines, β-lactams and even aziridines via this manifold have been reported.
AB - This article traces the development of catalytic, intramolecular dehydrogenative C-H amination (IDCA) reactions. Over the last 10 years, effective syntheses of carbazoles, indolines and oxindoles via palladium-catalyzed sp2 intramolecular dehydrogenative C-H amination reactions have been realized. While the corresponding amination reactions of sp3 C-H bonds are more challenging, syntheses of pyrrolidines, azetidines, β-lactams and even aziridines via this manifold have been reported.
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U2 - 10.1055/s-0034-1381051
DO - 10.1055/s-0034-1381051
M3 - Article
AN - SCOPUS:84946490133
SN - 0936-5214
VL - 26
SP - 2505
EP - 2511
JO - Synlett
JF - Synlett
IS - 18
M1 - st-2015-a0399-a
ER -