Synthesis and structure determination of N,N-diethyl-3-[3-aryl-1,2,4- oxadiazol-5-yl]propionamides

Rajendra Mohan Srivastava; Maria Da Conceição Pereira; Fernando Hallwass; Carlos R.N. Pacheco

doi:10.3987/com-99-8615

Synthesis and structure determination of N,N-diethyl-3-[3-aryl-1,2,4- oxadiazol-5-yl]propionamides

Rajendra Mohan Srivastava
, Maria Da Conceição Pereira
, Fernando Hallwass
, Carlos R.N. Pacheco

Chemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

An efficient and facile synthesis of six new 1,2,4-oxadiazoles (6a-f) with a tertiary amide group attached on the side-chain, in high yield, is described. Correct assignments of side-chain methylene, methyl protons, and carbon signals have been made with the assistance of COSY, NOESY and HETCOR NMR experiments.

Original language	English (US)
Pages (from-to)	2961-2967
Number of pages	7
Journal	Heterocycles
Volume	51
Issue number	12
DOIs	https://doi.org/10.3987/com-99-8615
State	Published - Dec 1 1999

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Pharmacology
Organic Chemistry

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abstract = "An efficient and facile synthesis of six new 1,2,4-oxadiazoles (6a-f) with a tertiary amide group attached on the side-chain, in high yield, is described. Correct assignments of side-chain methylene, methyl protons, and carbon signals have been made with the assistance of COSY, NOESY and HETCOR NMR experiments.",

author = "Srivastava, \{Rajendra Mohan\} and \{Da Concei{\c c}{\~a}o Pereira\}, Maria and Fernando Hallwass and Pacheco, \{Carlos R.N.\}",

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AU - Srivastava, Rajendra Mohan

AU - Da Conceição Pereira, Maria

AU - Hallwass, Fernando

AU - Pacheco, Carlos R.N.

PY - 1999/12/1

Y1 - 1999/12/1

N2 - An efficient and facile synthesis of six new 1,2,4-oxadiazoles (6a-f) with a tertiary amide group attached on the side-chain, in high yield, is described. Correct assignments of side-chain methylene, methyl protons, and carbon signals have been made with the assistance of COSY, NOESY and HETCOR NMR experiments.

AB - An efficient and facile synthesis of six new 1,2,4-oxadiazoles (6a-f) with a tertiary amide group attached on the side-chain, in high yield, is described. Correct assignments of side-chain methylene, methyl protons, and carbon signals have been made with the assistance of COSY, NOESY and HETCOR NMR experiments.

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DO - 10.3987/com-99-8615

M3 - Article

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JO - Heterocycles

JF - Heterocycles

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ER -

Synthesis and structure determination of N,N-diethyl-3-[3-aryl-1,2,4- oxadiazol-5-yl]propionamides

Abstract

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