Abstract
Bisphosphonates derived from natural terpenes were synthesized by phosphonylation of corresponding aldehydes. The general strategy of introduction of the phosphonate groups into the polyprenol molecule involves successive treatment of a hydroxyl compound by Swern reagent to oxidize the C-OH group into C=O and a (EtO)3P/[PyH]+ClO - 4 mixture to phosphylate the resulting carbonyl compound.
Original language | English (US) |
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Pages (from-to) | 647-653 |
Number of pages | 7 |
Journal | Russian Journal of General Chemistry |
Volume | 84 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2014 |
All Science Journal Classification (ASJC) codes
- General Chemistry