Synthesis of a high-affinity Fluorescent PPARγ ligand for high-throughput fluorescence polarization assays

Pharmacology, Toxicology and Pharmaceutical Science

• Peroxisome Proliferator Activated Receptor 100%
• Farglitazar 57%
• Malignant Neoplasm 14%
• Receptor 14%
• Disease 14%
• Inflammation 14%
• Receptor Subtype 14%
• Asthma 14%
• Atherosclerosis 14%
• Molecular Target 14%
• Fluorescein 14%
• Hormone Receptor 14%
• Transcription Factors 14%
• Multiple Sclerosis 14%
• Oxazole 14%
• Phenylacetylene 14%

Keyphrases

• Fluorescence Polarization Assay 100%
• Fluorescent Polarization 42%
• Protein Cavities 28%
• Propargylamines 14%
• Phenylacetylene 14%
• Scintillation Proximity Assay 14%
• Atherosclerosis Inflammation 14%
• Rational Ligand Design 14%
• Small Molecule Agonist 14%
• Receptor Probe 14%
• Oxazole 14%

Biochemistry, Genetics and Molecular Biology

• Peroxisome Proliferator-Activated Receptor 100%
• X Ray 28%
• Small Molecule 14%
• Transcription Factors 14%
• Agonist 14%
• Crystal Structure 14%
• Binding Competition 14%
• Nuclear Hormone Receptor 14%
• Fluorescein 14%
• Receptor Affinity 14%
• Ligand Binding Domain 14%