Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics

Oksana V. Aganova; Leysan F. Galiullina; Albert V. Aganov; Nikita V. Shtyrlin; Mikhail V. Pugachev; Alexey D. Strel'nik; Sergey A. Koshkin; Yurii G. Shtyrlin; Vladimir V. Klochkov

doi:10.1002/mrc.4378

Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics

Oksana V. Aganova, Leysan F. Galiullina, Albert V. Aganov, Nikita V. Shtyrlin, Mikhail V. Pugachev, Alexey D. Strel'nik, Sergey A. Koshkin, Yurii G. Shtyrlin, Vladimir V. Klochkov

Huck Institutes of the Life Sciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A novel phosphonium salt based on pyridoxine was synthesized. Conformational analysis of the compound in solution was performed using dynamic NMR experiments and calculations. The obtained results revealed some differences in the conformational transitions and the energy parameters of the conformational exchange of the studied compound in comparison to previously reported data for other phosphorus-containing pyridoxine derivatives. It was shown that increasing the substituent at the C-11 carbon leads to greater differences in the populations of stable states and the corresponding equilibrium energies.

Original language	English (US)
Pages (from-to)	320-327
Number of pages	8
Journal	Magnetic Resonance in Chemistry
Volume	54
Issue number	4
DOIs	https://doi.org/10.1002/mrc.4378
State	Published - Apr 1 2016

All Science Journal Classification (ASJC) codes

General Chemistry
General Materials Science

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title = "Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics",

abstract = "A novel phosphonium salt based on pyridoxine was synthesized. Conformational analysis of the compound in solution was performed using dynamic NMR experiments and calculations. The obtained results revealed some differences in the conformational transitions and the energy parameters of the conformational exchange of the studied compound in comparison to previously reported data for other phosphorus-containing pyridoxine derivatives. It was shown that increasing the substituent at the C-11 carbon leads to greater differences in the populations of stable states and the corresponding equilibrium energies.",

author = "Aganova, {Oksana V.} and Galiullina, {Leysan F.} and Aganov, {Albert V.} and Shtyrlin, {Nikita V.} and Pugachev, {Mikhail V.} and Strel'nik, {Alexey D.} and Koshkin, {Sergey A.} and Shtyrlin, {Yurii G.} and Klochkov, {Vladimir V.}",

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year = "2016",

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doi = "10.1002/mrc.4378",

language = "English (US)",

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TY - JOUR

T1 - Synthesis of a new quaternary phosphonium salt

T2 - NMR study of the conformational structure and dynamics

AU - Aganova, Oksana V.

AU - Galiullina, Leysan F.

AU - Aganov, Albert V.

AU - Shtyrlin, Nikita V.

AU - Pugachev, Mikhail V.

AU - Strel'nik, Alexey D.

AU - Koshkin, Sergey A.

AU - Shtyrlin, Yurii G.

AU - Klochkov, Vladimir V.

PY - 2016/4/1

Y1 - 2016/4/1

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AB - A novel phosphonium salt based on pyridoxine was synthesized. Conformational analysis of the compound in solution was performed using dynamic NMR experiments and calculations. The obtained results revealed some differences in the conformational transitions and the energy parameters of the conformational exchange of the studied compound in comparison to previously reported data for other phosphorus-containing pyridoxine derivatives. It was shown that increasing the substituent at the C-11 carbon leads to greater differences in the populations of stable states and the corresponding equilibrium energies.

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JO - Magnetic Resonance in Chemistry

JF - Magnetic Resonance in Chemistry

IS - 4

ER -

Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics

Abstract

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