Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid

Thomas A. Lessen; Donald M. Demko; Steven M. Weinreb

doi:10.1016/0040-4039(90)80083-X

Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid

Thomas A. Lessen, Donald M. Demko, Steven M. Weinreb

Chemistry

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

A key intramolecular N-acyliminium ion/silylenol ether cyclization of 17, derived from L-glutamic acid, has been used to construct the bridged bicyclic quinocarcin intermediate 3.

Original language	English (US)
Pages (from-to)	2105-2108
Number of pages	4
Journal	Tetrahedron Letters
Volume	31
Issue number	15
DOIs	https://doi.org/10.1016/0040-4039(90)80083-X
State	Published - 1990

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(90)80083-X

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title = "Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid",

abstract = "A key intramolecular N-acyliminium ion/silylenol ether cyclization of 17, derived from L-glutamic acid, has been used to construct the bridged bicyclic quinocarcin intermediate 3.",

author = "Lessen, {Thomas A.} and Demko, {Donald M.} and Weinreb, {Steven M.}",

year = "1990",

doi = "10.1016/0040-4039(90)80083-X",

language = "English (US)",

volume = "31",

pages = "2105--2108",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

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T1 - Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid

AU - Lessen, Thomas A.

AU - Demko, Donald M.

AU - Weinreb, Steven M.

PY - 1990

Y1 - 1990

N2 - A key intramolecular N-acyliminium ion/silylenol ether cyclization of 17, derived from L-glutamic acid, has been used to construct the bridged bicyclic quinocarcin intermediate 3.

AB - A key intramolecular N-acyliminium ion/silylenol ether cyclization of 17, derived from L-glutamic acid, has been used to construct the bridged bicyclic quinocarcin intermediate 3.

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U2 - 10.1016/0040-4039(90)80083-X

DO - 10.1016/0040-4039(90)80083-X

M3 - Article

AN - SCOPUS:0025217328

SN - 0040-4039

VL - 31

SP - 2105

EP - 2108

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid

Abstract

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