Synthesis of lipophilic N-phosphorylmethylated amino acids and their membrane-transport properties towards some organic acids

Rafael A. Cherkasov, Sergey A. Koshkin, Airat R. Garifzyanov, Natal'ya V. Davletshina

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

One-pot procedureswere developed for the synthesis of lipophilic N-(dialkylphosphorylmethyl) derivatives of natural amino acids with high yields from dioctyloxide, formaldehyde, and an amino acid in the presence of amino acid hydrochloride.Membrane transport properties of the new phosphorylated amino acids towards polyfunctional carboxylic acidswere studied. Itwas found that N,N-bis[(dioctylphosphoryl)methyl]- β-alanine is a selective extractant for glutaric acid.

Original languageEnglish (US)
Pages (from-to)1650-1651
Number of pages2
JournalPhosphorus, Sulfur and Silicon and the Related Elements
Volume191
Issue number11-12
DOIs
StatePublished - Dec 1 2016

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Inorganic Chemistry

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