Synthesis of two bi-functional ligands for the QUEST three-hybrid system

S. J. Baker; S. M. Firestine; D. Smithrud; F. Salinas; S. J. Benkovic

doi:10.1016/S0040-4039(00)01202-8

Synthesis of two bi-functional ligands for the QUEST three-hybrid system

S. J. Baker
, S. M. Firestine
, D. Smithrud
, F. Salinas
, S. J. Benkovic

Chemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The synthesis is described for two bi-functional ligands (1) and (2) that have been used as chemical inducers of dimerization for QUEST,¹ a three-hybrid system designed to detect novel enzyme activity in vivo. (C) 2000 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	7009-7012
Number of pages	4
Journal	Tetrahedron Letters
Volume	41
Issue number	36
DOIs	https://doi.org/10.1016/S0040-4039(00)01202-8
State	Published - Sep 2 2000

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)01202-8

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title = "Synthesis of two bi-functional ligands for the QUEST three-hybrid system",

abstract = "The synthesis is described for two bi-functional ligands (1) and (2) that have been used as chemical inducers of dimerization for QUEST,1 a three-hybrid system designed to detect novel enzyme activity in vivo. (C) 2000 Elsevier Science Ltd.",

author = "Baker, \{S. J.\} and Firestine, \{S. M.\} and D. Smithrud and F. Salinas and Benkovic, \{S. J.\}",

note = "Funding Information: We gratefully acknowledge Douglas Jordon and Gregory Basarab (DuPont) for information and materials. S.M.F. was funded by a fellowship from the Damon Runyon–Walter Winchell foundation and F.S. was funded by a fellowship from the National Institutes of Health.",

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doi = "10.1016/S0040-4039(00)01202-8",

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journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Synthesis of two bi-functional ligands for the QUEST three-hybrid system

AU - Baker, S. J.

AU - Firestine, S. M.

AU - Smithrud, D.

AU - Salinas, F.

AU - Benkovic, S. J.

N1 - Funding Information: We gratefully acknowledge Douglas Jordon and Gregory Basarab (DuPont) for information and materials. S.M.F. was funded by a fellowship from the Damon Runyon–Walter Winchell foundation and F.S. was funded by a fellowship from the National Institutes of Health.

PY - 2000/9/2

Y1 - 2000/9/2

N2 - The synthesis is described for two bi-functional ligands (1) and (2) that have been used as chemical inducers of dimerization for QUEST,1 a three-hybrid system designed to detect novel enzyme activity in vivo. (C) 2000 Elsevier Science Ltd.

AB - The synthesis is described for two bi-functional ligands (1) and (2) that have been used as chemical inducers of dimerization for QUEST,1 a three-hybrid system designed to detect novel enzyme activity in vivo. (C) 2000 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0034596465

UR - https://www.scopus.com/pages/publications/0034596465#tab=citedBy

U2 - 10.1016/S0040-4039(00)01202-8

DO - 10.1016/S0040-4039(00)01202-8

M3 - Article

AN - SCOPUS:0034596465

SN - 0040-4039

VL - 41

SP - 7009

EP - 7012

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 36

ER -

Synthesis of two bi-functional ligands for the QUEST three-hybrid system

Abstract

All Science Journal Classification (ASJC) codes

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