System for analyzing high-resolution three-dimensional coronary angiograms

William E. Higgins, Wolfgang J.T. Spyra, Ronald A. Karwoski, Erik L. Ritman

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


Three-dimensional (3-D) high-resolution coronary angiograms offer a means for visualizing the entire coronary arterial tree from any orientation and for detecting and quantitating coronary arterial stenoses. Previously, a skilled operator had to perform several hours of tedious manual analysis using an interactive graphical user-interface (GUI) system (Treu Trace) to analyze a 3-D angiogram. We have devised an improved GUI system, consisting of three tools for analyzing 3-D angiograms. The Artery Extractor first performs automatic image-analysis operations to extract the central axes of the arterial tree. Next, using the Artery Display tool and results from the Artery Extractor, the operator can visualize structures in the angiogram and compute various measurements. Finally, the aforementioned Tree Trace tool can be used to manually correct irregularities in the automatically generated results of the Artery Extractor. The system greatly reduces operator analysis time, gives exactly reproducible results, uses true 3-D image-processing operations, and provides a comprehensive interface for visualizing and quantifying features of the 3-D coronary arteries.

Original languageEnglish (US)
Pages (from-to)377-385
Number of pages9
JournalIEEE transactions on medical imaging
Issue number3
StatePublished - 1996

All Science Journal Classification (ASJC) codes

  • Software
  • Radiological and Ultrasound Technology
  • Computer Science Applications
  • Electrical and Electronic Engineering


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