@article{a0c07db43dbb49adac6c88e17d7ffd5e,
title = "T3P-promoted synthesis of a series of novel 2-aryl-3-phenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones",
abstract = "A series of twelve novel 2-aryl-3-phenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones was prepared at room temperature by T3P-mediated cyclization of C-aryl-N-phenyl imines with 3-mercaptopropionic acid. The reaction can also be run as a 3-component reaction, forming the imine in situ. The reactions were operationally simple, rapid and gave yields as high as 75%. This provides ready access to C-aryl-N-phenyl compounds in this family, which have been generally difficult to prepare.",
author = "Silverberg, {Lee J.} and Carlos Pacheco and Debashish Sahu and Tapas Mal and Peter Scholl and Sobhi, {Hany F.} and Bradley, {Heather G.} and Cardenas, {Omar A.} and Gonzalez, {Kyanna M.} and Islam, {Jasra M.} and Kimmel, {Emily G.} and Winnie Li and Perhonitch, {Kristen C.} and Pothering, {Jennifer T.} and Potts, {Michael E.} and Ramirez, {Melissa E.} and Reppert, {Haley E.} and Shaffer, {Kelsey N.}",
note = "Funding Information: The authors thank Euticals , Inc. (AMRI) for the gift of T3P in 2-methyltetrahydrofuran, and Penn State Schuylkill for financial support. We also thank Bill Smith of Albany Molecular Research Inc. for suggesting catalytic T3P. Funding Information: The authors thank Euticals, Inc. (AMRI) for the gift of T3P in 2-methyltetrahydrofuran, and Penn State Schuylkill for financial support. We also thank Bill Smith of Albany Molecular Research Inc. for suggesting catalytic T3P. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = apr,
day = "30",
doi = "10.1016/j.tetlet.2020.151836",
language = "English (US)",
volume = "61",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "18",
}