T3P-promoted synthesis of a series of novel 3-aryl-2-phenyl-2,3-dihydro-4H-1,3-benzothiazin-4-ones

  • Lee J. Silverberg
  • , Carlos Pacheco
  • , Debashish Sahu
  • , Peter Scholl
  • , Hany F. Sobhi
  • , Joshua T. Bachert
  • , Kaitlyn Bandholz
  • , Ryan V. Bendinsky
  • , Heather G. Bradley
  • , Baylee K. Colburn
  • , David J. Coyle
  • , Jonathon R. Dahl
  • , Megan Felty
  • , Ryan F. Fox
  • , Kyanna M. Gonzalez
  • , Jasra M. Islam
  • , Stacy E. Koperna
  • , Quentin J. Moyer
  • , Duncan J. Noble
  • , Melissa E. Ramirez
  • Ziwei Yang

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A series of 11 novel 3-aryl-2-phenyl-2,3-dihydro-4H-1,3-benzothiazin-4-ones was prepared at room temperature by T3P-mediated cyclization of N-aryl-C-phenyl imines with thiosalicylic acid. This provides simple and ready access to N-aryl compounds in this family, which have been generally difficult to prepare.

Original languageEnglish (US)
Pages (from-to)1797-1805
Number of pages9
JournalJournal of Heterocyclic Chemistry
Volume57
Issue number4
DOIs
StatePublished - Apr 1 2020

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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